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Side effects from oxytocin are rare. Potential side effects of oxytocin include:
Potential side effects from tadalafil include:
Potential side effects from PT-141 include:
Grapefruit and grapefruit juice affect how tadalafil (one of the components of Passion+) is metabolized. Grapefruit juice can decrease the metabolism of tadalafil and increase its level in the blood. Grapefruit will decrease the enzyme CYP3A4, which breaks down tadalafil and releases it in a controlled dosage in your body.
Grapefruit can take 72 hours to metabolize. Do not consume grapefruit while taking tadalafil.
Potential side effects of combining grapefruit and tadalafil:
Yes, in the United States, compounded medications are only available by prescription. A prescription is required to ensure that you do not have any contraindications for the medications.
Oral ED medications, such as tadalafil, work by increasing blood flow into the penis. Sexual stimulation is required, then a cascade of chemical reactions occurs. The end result is the relaxation of smooth muscle lining blood vessels and the chambers in the penis. This increases blood flow into the penis.
PT-141 is a synthetic peptide that binds to and activates the melanocortin receptors in the brain. After binding, it increases sexual arousal.
Tadalafil takes 30 to 60 minutes to take effect. The time it takes for PT-141 to have its full effect varies, but it can take minutes to an hour. Passion+ can have effects lasting up to 36 hours.
PT-141 acts in the brain to increase sexual desire and improve erectile function. After sexual stimulation, tadalafil increases blood flow into the penis and clitoris to increase arousal and the likelihood of orgasm. Oxytocin increases satisfaction with sexual intimacy. Each of the three drugs has a role in improving sexual satisfaction.
*Prescription medications available only if prescribed by the healthcare provider after an online consultation. This is a compounded medication.